Llwytho...
Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1
The RNA binding protein Celf1 regulates alternative splicing in the nucleus and mRNA stability and translation in the cytoplasm. Celf1 is strongly down-regulated during mouse postnatal heart development. Its re-induction in adults induced severe heart failure and reversion to fetal splicing and gene...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Sci Rep |
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Prif Awduron: | , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Nature Publishing Group
2016
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5069560/ https://ncbi.nlm.nih.gov/pubmed/27759042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35550 |
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