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Wall Teichoic Acids Are Involved in the Medium-Induced Loss of Function of the Autolysin CD11 against Clostridium difficile

Bacterial lysins are potent antibacterial enzymes with potential applications in the treatment of bacterial infections. Some lysins lose activity in the growth media of target bacteria, and the underlying mechanism remains unclear. Here we use CD11, an autolysin of Clostridium difficile, as a model...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Wu, Xia, Paskaleva, Elena E., Mehta, Krunal K., Dordick, Jonathan S., Kane, Ravi S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069495/
https://ncbi.nlm.nih.gov/pubmed/27759081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35616
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