Live-cell imaging of ER-PM contact architecture by a novel TIRFM approach reveals extension of junctions in response to store-operated Ca(2+)-entry

Nanometer-spaced appositions between endoplasmic reticulum and plasma membrane (ER-PM junctions) stabilized by membrane-joining protein complexes are critically involved in cellular Ca(2+)-handling and lipid trafficking. ER-PM junctional architecture and plasticity associated with inter-membrane com...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Poteser, Michael, Leitinger, Gerd, Pritz, Elisabeth, Platzer, Dieter, Frischauf, Irene, Romanin, Christoph, Groschner, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069484/
https://ncbi.nlm.nih.gov/pubmed/27759093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35656
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