A rare subset of skin-tropic regulatory T cells expressing Il10/Gzmb inhibits the cutaneous immune response

Foxp3(+) regulatory T cells (Tregs) migrating from the skin to the draining lymph node (dLN) have a strong immunosuppressive effect on the cutaneous immune response. However, the subpopulations responsible for their inhibitory function remain unclear. We investigated single-cell gene expression hete...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ikebuchi, Ryoyo, Teraguchi, Shunsuke, Vandenbon, Alexis, Honda, Tetsuya, Shand, Francis H. W., Nakanishi, Yasutaka, Watanabe, Takeshi, Tomura, Michio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069467/
https://ncbi.nlm.nih.gov/pubmed/27756896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35002
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