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Dmp1 Null Mice Develop a Unique Osteoarthritis-like Phenotype

Patients with hypophosphatemia rickets (including DMP1 mutations) develop severe osteoarthritis (OA), although the mechanism is largely unknown. In this study, we first identified the expression of DMP1 in hypertrophic chondrocytes using immunohistochemistry (IHC) and X-gal analysis of Dmp1-knockout...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Zhang, Qi, Lin, Shuxian, Liu, Ying, Yuan, Baozhi, Harris, Steph E, Feng, Jian Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069442/
https://ncbi.nlm.nih.gov/pubmed/27766035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.15833
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