Sustained Release of Protein Therapeutics from Subcutaneous Thermosensitive Biocompatible and Biodegradable Pentablock Copolymers (PTSgels)

Objective. To evaluate thermosensitive, biodegradable pentablock copolymers (PTSgel) for sustained release and integrity of a therapeutic protein when injected subcutaneously. Materials and Methods. Five PTSgels with PEG-PCL-PLA-PCL-PEG block arrangements were synthesized. In vitro release of IgG fr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Drug Deliv
Main Authors: Schaefer, Elizabeth, Abbaraju, Santhi, Walsh, Mary, Newman, Donna, Salmon, Jacklyn, Amin, Rasidul, Weiss, Sidney, Grau, Ulrich, Velagaleti, Poonam, Gilger, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069382/
https://ncbi.nlm.nih.gov/pubmed/27800184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2407459
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados