Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives

A series of novel quaternary ammonium 4-deoxypyridoxine derivatives was synthesized. Two compounds demonstrated excellent activity against a panel of Gram-positive methicillin-resistant S. aureus strains with MICs in the range of 0.5–2 μg/mL, exceeding the activity of miramistin. At the same time, b...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Shtyrlin, Nikita V., Sapozhnikov, Sergey V., Galiullina, Albina S., Kayumov, Airat R., Bondar, Oksana V., Mirchink, Elena P., Isakova, Elena B., Firsov, Alexander A., Balakin, Konstantin V., Shtyrlin, Yurii G.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069379/
https://ncbi.nlm.nih.gov/pubmed/27800491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3864193
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