Induction of Cellular Immune Responses to Simian Immunodeficiency Virus Gag by Two Recombinant Negative-Strand RNA Virus Vectors

A recombinant Newcastle disease virus (rNDV) expressing simian immunodeficiency virus (SIV) Gag protein (rNDV/SIVgag) was generated. The rNDV/SIVgag virus induced Gag-specific cellular immune responses in mice, leading to a specific anti-Gag antiviral immunity. This was evidenced by the inhibition o...

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Detalhes bibliográficos
Main Authors: Nakaya, Yurie, Nakaya, Takaaki, Park, Man-Seong, Cros, Jerome, Imanishi, Jiro, Palese, Peter, García-Sastre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC506935/
https://ncbi.nlm.nih.gov/pubmed/15308731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.17.9366-9375.2004
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