Human Cytomegalovirus UL84 Oligomerization and Heterodimerization Domains Act as Transdominant Inhibitors of oriLyt-Dependent DNA Replication: Evidence that IE2-UL84 and UL84-UL84 Interactions Are Required for Lytic DNA Replication

Human cytomegalovirus (HCMV) UL84 encodes a 75-kDa protein required for oriLyt-dependent DNA replication and interacts with IE2 in infected and transfected cells. UL84 localizes to the nucleus of transfected and infected cells and is found in viral replication compartments. In transient assays it wa...

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Main Authors: Colletti, Kelly S., Xu, Yiyang, Cei, Sylvia A., Tarrant, Margaret, Pari, Gregory S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC506931/
https://ncbi.nlm.nih.gov/pubmed/15308715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.17.9203-9214.2004
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