Wild-type p53 binds to the TATA-binding protein and represses transcription.

Lignende værker

• Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression.
  af: Horikoshi, N, et al.
  Udgivet: (1995)
• Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein.
  af: Farmer, G, et al.
  Udgivet: (1996)
• Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription.
  af: Lechner, M S, et al.
  Udgivet: (1992)
• The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription.
  af: Liu, X, et al.
  Udgivet: (1993)
• Repression of the basal c-fos promoter by wild-type p53.
  af: Kley, N, et al.
  Udgivet: (1992)