Mood changes in cognitively normal older adults are linked to Alzheimer’s disease biomarker levels

OBJECTIVES: To evaluate whether cerebrospinal fluid (CSF) and PET Pittsburgh Compound B (PiB) biomarkers of underlying Alzheimer disease (AD) pathology (β-amyloid(42) [Aβ(42)], tau, phosphorylated tau(181) [ptau(181)], tau/Aβ(42), ptau(181)/Aβ(42) and mean cortical binding potential [MCBP] for PET-P...

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Udgivet i:Am J Geriatr Psychiatry
Main Authors: Babulal, Ganesh M., Ghoshal, Nupur, Head, Denise, Vernon, Elizabeth K., Holtzman, David M., Benzinger, Tammie L. S., Fagan, Anne M., Morris, John C., Roe, Catherine M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069099/
https://ncbi.nlm.nih.gov/pubmed/27426238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jagp.2016.04.004
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