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Molecular mechanisms of regulation of Toll-like receptor signaling

TLRs play a critical role in the detection of microbes and endogenous “alarmins” to initiate host defense, yet they can also contribute to the development and progression of inflammatory and autoimmune diseases. To avoid pathogenic inflammation, TLR signaling is subject to multilayer regulatory cont...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Leifer, Cynthia A., Medvedev, Andrei E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069093/
https://ncbi.nlm.nih.gov/pubmed/27343013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2MR0316-117RR
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