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Epigenomic profiling of preterm infants reveals DNA methylation differences at sites associated with neural function

DNA methylation (DNAm) plays a determining role in neural cell fate and provides a molecular link between early-life stress and neuropsychiatric disease. Preterm birth is a profound environmental stressor that is closely associated with alterations in connectivity of neural systems and long-term neu...

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Publicat a:Transl Psychiatry
Autors principals: Sparrow, S, Manning, J R, Cartier, J, Anblagan, D, Bastin, M E, Piyasena, C, Pataky, R, Moore, E J, Semple, S I, Wilkinson, A G, Evans, M, Drake, A J, Boardman, J P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068883/
https://ncbi.nlm.nih.gov/pubmed/26784970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.210
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