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Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection.

Mice with a targeted disruption in the beta 2-microglobulin (beta 2m) gene, which lack major histocompatibility complex class I molecules and consequently fail to develop functional CD8 T cells, provided a useful model for assessing the role of class I-restricted T cells in resistance to infection w...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Flynn, J L, Goldstein, M M, Triebold, K J, Koller, B, Bloom, B R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50688/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1465432/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.12013
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