Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection.
Mice with a targeted disruption in the beta 2-microglobulin (beta 2m) gene, which lack major histocompatibility complex class I molecules and consequently fail to develop functional CD8 T cells, provided a useful model for assessing the role of class I-restricted T cells in resistance to infection w...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50688/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1465432/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.12013 |
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