Neuroplasticity-dependent and -independent mechanisms of chronic deep brain stimulation in stressed rats

Chronic ventromedial prefrontal cortex (vmPFC) deep brain stimulation (DBS) improves depressive-like behaviour in rats via serotonergic and neurotrophic-related mechanisms. We hypothesise that, in addition to these substrates, DBS-induced increases in hippocampal neurogenesis may also be involved. O...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Bambico, F R, Bregman, T, Diwan, M, Li, J, Darvish-Ghane, S, Li, Z, Laver, B, Amorim, B O, Covolan, L, Nobrega, J N, Hamani, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068759/
https://ncbi.nlm.nih.gov/pubmed/26529427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.166
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