Inhibition of the Membrane Attack Complex by Dengue Virus NS1 through Interaction with Vitronectin and Terminal Complement Proteins

Dengue virus (DENV) infects millions of people worldwide and is a major public health problem. DENV nonstructural protein 1 (NS1) is a conserved glycoprotein that associates with membranes and is also secreted into the plasma in DENV-infected patients. The present study describes a novel mechanism b...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Conde, Jonas Nascimento, da Silva, Emiliana Mandarano, Allonso, Diego, Coelho, Diego Rodrigues, Andrade, Iamara da Silva, de Medeiros, Luciano Neves, Menezes, Joice Lima, Barbosa, Angela Silva, Mohana-Borges, Ronaldo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068511/
https://ncbi.nlm.nih.gov/pubmed/27512066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00912-16
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