Advanced Glycation End Products and its Soluble Receptors in the Pathogenesis of Thoracic Aortic Aneurysm

BACKGROUND: Matrix metalloproteinases (MMPs) have been implicated in the pathogenesis of thoracic aortic aneurysms (TAAs). Cytokines [Interleukin (IL)-Iβ, IL-2, IL-6, and TNF-α)] increase the expression of MMP-2 and -3. Advanced glycation end products (AGEs) interact with cell receptors to increase...

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Foilsithe in:Aorta (Stamford)
Main Authors: Prasad, Kailash, Sarkar, Abdullah, Zafar, Mohammad A., Shoker, Ahmed, Moselhi, Hamdi EI, Tranquilli, Maryann, Ziganshin, Bulat A., Elefteriades, John A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Science International Corporation 2016
Ábhair:
Original Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068493/
https://ncbi.nlm.nih.gov/pubmed/27766267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12945/j.aorta.2015.15.018
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