Inhibition of microRNA-34a prevents IL-1β-induced extracellular matrix degradation in nucleus pulposus by increasing GDF5 expression

Accumulating evidence indicates that miRNAs, a class of small non-coding RNAs, are implicated in the pathogenesis of various diseases such as cancer and intervertebral disc degeneration. The aim of this study was to investigate the expression and the biological function of microRNA-34a in interverte...

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Dades bibliogràfiques
Publicat a:Exp Biol Med (Maywood)
Autors principals: Liu, Wei, Zhang, Yukun, Feng, Xintong, Li, Shuai, Gao, Yong, Wang, Kun, Song, Yu, Yang, Shuhua, Tu, Ji, Shao, Zengwu, Yang, Cao
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068468/
https://ncbi.nlm.nih.gov/pubmed/27385596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216657444
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