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Inhibition of microRNA-34a prevents IL-1β-induced extracellular matrix degradation in nucleus pulposus by increasing GDF5 expression

Accumulating evidence indicates that miRNAs, a class of small non-coding RNAs, are implicated in the pathogenesis of various diseases such as cancer and intervertebral disc degeneration. The aim of this study was to investigate the expression and the biological function of microRNA-34a in interverte...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Liu, Wei, Zhang, Yukun, Feng, Xintong, Li, Shuai, Gao, Yong, Wang, Kun, Song, Yu, Yang, Shuhua, Tu, Ji, Shao, Zengwu, Yang, Cao
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068468/
https://ncbi.nlm.nih.gov/pubmed/27385596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216657444
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