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An evolutionarily conserved element in initiator tRNAs prompts ultimate steps in ribosome maturation

Ribosome biogenesis, a complex multistep process, results in correct folding of rRNAs, incorporation of >50 ribosomal proteins, and their maturation. Deficiencies in ribosome biogenesis may result in varied faults in translation of mRNAs causing cellular toxicities and ribosomopathies in higher o...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Shetty, Sunil, Varshney, Umesh
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068261/
https://ncbi.nlm.nih.gov/pubmed/27698115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609550113
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