IL-6 promotes the differentiation of a subset of naive CD8(+) T cells into IL-21–producing B helper CD8(+) T cells

IL-6 is known to contribute to the differentiation of CD4(+) T cells into different subsets of effector T helper cells. Less is known about the potential of IL-6 in regulating CD8(+) T cell effector function. Here, we identify IL-6 as a master regulator of IL-21 in effector CD8(+) T cells. IL-6 prom...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Med
Hauptverfasser: Yang, Rui, Masters, April R., Fortner, Karen A., Champagne, Devin P., Yanguas-Casás, Natalia, Silberger, Daniel J., Weaver, Casey T., Haynes, Laura, Rincon, Mercedes
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068236/
https://ncbi.nlm.nih.gov/pubmed/27670591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160417
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