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Multivalent Chromosomal Expression of the Clostridium botulinum Serotype A Neurotoxin Heavy-Chain Antigen and the Bacillus anthracis Protective Antigen in Lactobacillus acidophilus

Clostridium botulinum and Bacillus anthracis produce potent toxins that cause severe disease in humans. New and improved vaccines are needed for both of these pathogens. For mucosal vaccine delivery using lactic acid bacteria, chromosomal expression of antigens is preferred over plasmid-based expres...

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Bibliografiset tiedot
Julkaisussa:Appl Environ Microbiol
Päätekijät: O'Flaherty, Sarah, Klaenhammer, Todd R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068166/
https://ncbi.nlm.nih.gov/pubmed/27496774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01533-16
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