Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin

Background: The dual oxidases (Duox) are involved in hydrogen peroxide generation, which is essential for thyroid hormone synthesis, and therefore they are markers of thyroid function. During inflammation, cytokines upregulate DUOX gene expression in the airway and the intestine, suggesting a role f...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Eskalli, Zineb, Achouri, Younes, Hahn, Stephan, Many, Marie-Christine, Craps, Julie, Refetoff, Samuel, Liao, Xiao-Hui, Dumont, Jacques E., Van Sande, Jacqueline, Corvilain, Bernard, Miot, Françoise, De Deken, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067804/
https://ncbi.nlm.nih.gov/pubmed/27599561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2016.0106
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