Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner

Apigenin (APG) is an edible plant-derived flavonoid that shows modest antitumor activities in vitro and in vivo. APG treatment results in cell growth arrest and apoptosis in various types of tumors by modulating several signaling pathways. In the present study, we evaluated interactions between APG...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Chen, Minghui, Wang, Xueshi, Zha, Daolong, Cai, Fangfang, Zhang, Wenjing, He, Yan, Huang, Qilai, Zhuang, Hongqin, Hua, Zi-Chun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067669/
https://ncbi.nlm.nih.gov/pubmed/27752089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35468
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires