Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner

Apigenin (APG) is an edible plant-derived flavonoid that shows modest antitumor activities in vitro and in vivo. APG treatment results in cell growth arrest and apoptosis in various types of tumors by modulating several signaling pathways. In the present study, we evaluated interactions between APG...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Minghui, Wang, Xueshi, Zha, Daolong, Cai, Fangfang, Zhang, Wenjing, He, Yan, Huang, Qilai, Zhuang, Hongqin, Hua, Zi-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067669/
https://ncbi.nlm.nih.gov/pubmed/27752089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35468
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