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DNA damage precedes apoptosis during the regression of the interdigital tissue in vertebrate embryos

DNA damage independent of caspase activation accompanies programmed cell death in different vertebrate embryonic organs. We analyzed the significance of DNA damage during the regression of the interdigital tissue, which sculpts the digits in the embryonic limb. Interdigit remodeling involves oxidati...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Montero, Juan A., Sanchez-Fernandez, Cristina, Lorda-Diez, Carlos I., Garcia-Porrero, Juan A., Hurle, Juan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067507/
https://ncbi.nlm.nih.gov/pubmed/27752097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35478
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