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Effectiveness of tyrosine kinase inhibitors on uncommon E709X epidermal growth factor receptor mutations in non-small-cell lung cancer

BACKGROUND: Clinical features of epidermal growth factor receptor (EGFR) mutations: L858R, deletions in exon 19, T790M, insertions in exon 20, G719X, and L861X in non-small-cell lung cancer (NSCLC) are well-known. The clinical significance of other uncommon EGFR mutations, such as E709X, is not well...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Wu, Jenn-Yu, Shih, Jin-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067004/
https://ncbi.nlm.nih.gov/pubmed/27785061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S118071
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