A Quorum Sensing Signal Promotes Host Tolerance Training Through HDAC1-Mediated Epigenetic Reprogramming

The mechanisms by which pathogens evade elimination without affecting host fitness are not well understood. For the pathogen Pseudomonas aeruginosa, this evasion appears to be triggered by excretion of the quorum sensing (QS) molecule 2-aminoacetophenone (2-AA), which dampens host immune responses a...

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Vydáno v:Nat Microbiol
Hlavní autoři: Bandyopadhaya, Arunava, Tsurumi, Amy, Maura, Damien, Jeffrey, Kate L., Rahme, Laurence G
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066596/
https://ncbi.nlm.nih.gov/pubmed/27694949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.174
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