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Molecular mimicry of hepatitis B surface antigen by an anti-idiotype-derived synthetic peptide.

Monoclonal antibody 2F10 is an "internal-image" anti-idiotype (anti-id) antibody capable of mimicking the group-specific "a" determinant of human hepatitis B surface antigen (HBsAg). By mRNA sequencing and computer-assisted molecular modeling of monoclonal antibody 2F10, we identified a 15-amino aci...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Pride, M W, Shi, H, Anchin, J M, Linthicum, D S, LoVerde, P T, Thakur, A, Thanavala, Y
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50665/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1361231/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.11900
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