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Plasmids from Shiga Toxin-Producing Escherichia coli Strains with Rare Enterohemolysin Gene (ehxA) Subtypes Reveal Pathogenicity Potential and Display a Novel Evolutionary Path

Most Shiga toxin-producing Escherichia coli (STEC) strains associated with severe disease, such as hemolytic-uremic syndrome (HUS), carry large enterohemolysin-encoding (ehxA) plasmids, e.g., pO157 and pO103, that contribute to STEC clinical manifestations. Six ehxA subtypes (A through F) exist that...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Lorenz, Sandra C., Monday, Steven R., Hoffmann, Maria, Fischer, Markus, Kase, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066353/
https://ncbi.nlm.nih.gov/pubmed/27542930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01839-16
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