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A simple and efficient method to visualize and quantify the efficiency of chromosomal mutations from genome editing
Genome editing with designer nucleases such as TALEN and CRISPR/Cas enzymes has broad applications. Delivery of these designer nucleases into organisms induces various genetic mutations including deletions, insertions and nucleotide substitutions. Characterizing those mutations is critical for evalu...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5066342/ https://ncbi.nlm.nih.gov/pubmed/27748423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35488 |
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