Effective gene expression in the rat dorsal root ganglia with a non-viral vector delivered via spinal nerve injection

Delivering gene constructs into the dorsal root ganglia (DRG) is a powerful but challenging therapeutic strategy for sensory disorders affecting the DRG and their peripheral processes. The current delivery methods of direct intra-DRG injection and intrathecal injection have several disadvantages, in...

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Udgivet i:Sci Rep
Main Authors: Chang, Ming-Fong, Hsieh, Jung-Hsien, Chiang, Hao, Kan, Hung-Wei, Huang, Cho-Min, Chellis, Luke, Lin, Bo-Shiou, Miaw, Shi-Chuen, Pan, Chun-Liang, Chao, Chi-Chao, Hsieh, Sung-Tsang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066268/
https://ncbi.nlm.nih.gov/pubmed/27748450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35612
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