The primary transcriptome of the Escherichia coli O104:H4 pAA plasmid and novel insights into its virulence gene expression and regulation

Escherichia coli O104:H4 (E. coli O104:H4), which caused a massive outbreak of acute gastroenteritis and hemolytic uremic syndrome in 2011, carries an aggregative adherence fimbriae I (AAF/I) encoding virulence plasmid, pAA. The importance of pAA in host-pathogen interaction and disease severity has...

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Udgivet i:Sci Rep
Main Authors: Berger, Petya, Knödler, Michael, Förstner, Konrad U., Berger, Michael, Bertling, Christian, Sharma, Cynthia M., Vogel, Jörg, Karch, Helge, Dobrindt, Ulrich, Mellmann, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066232/
https://ncbi.nlm.nih.gov/pubmed/27748404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35307
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