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Orexin-1 receptor blockade suppresses compulsive-like alcohol drinking in mice

Addiction is promoted by pathological motivation for addictive substances, and, despite extensive efforts, alcohol use disorders (AUDs) continue to extract a very high social, physical, and economic toll. Compulsive drinking of alcohol, where consumption persists even when alcohol is paired with neg...

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Veröffentlicht in:Neuropharmacology
Hauptverfasser: Lei, Kelly, Wegner, Scott A., Yu, Ji-Hwan, Hopf, F. Woodward
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065938/
https://ncbi.nlm.nih.gov/pubmed/27523303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.08.008
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