Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation

Genome-wide association studies (GWASs) have revealed increased breast cancer risk associated with multiple genetic variants at 5p12. Here, we report the fine mapping of this locus using data from 104,660 subjects from 50 case-control studies in the Breast Cancer Association Consortium (BCAC). With...

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I publikationen:Am J Hum Genet
Huvudupphovsmän: Ghoussaini, Maya, French, Juliet D., Michailidou, Kyriaki, Nord, Silje, Beesley, Jonathan, Canisus, Sander, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lee, Jason S., Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Milne, Roger L., Hopper, John L., Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Muir, Kenneth, Lophatananon, Artitaya, Fasching, Peter A., Beckmann, Matthias W., Fletcher, Olivia, Johnson, Nichola, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara, Marme, Frederik, Guénel, Pascal, Truong, Thérèse, Bojesen, Stig E., Flyger, Henrik, Benitez, Javier, González-Neira, Anna, Alonso, M. Rosario, Pita, Guillermo, Neuhausen, Susan L., Anton-Culver, Hoda, Brenner, Hermann, Arndt, Volker, Meindl, Alfons, Schmutzler, Rita K., Brauch, Hiltrud, Hamann, Ute, Tessier, Daniel C., Vincent, Daniel, Nevanlinna, Heli, Khan, Sofia, Matsuo, Keitaro, Ito, Hidemi, Dörk, Thilo, Bogdanova, Natalia V., Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kosma, Veli-Matti, Wu, Anna H., Van Den Berg, David, Lambrechts, Diether, Floris, Giuseppe, Chang-Claude, Jenny, Rudolph, Anja, Radice, Paolo, Barile, Monica, Couch, Fergus J., Hallberg, Emily, Giles, Graham G., Haiman, Christopher A., Le Marchand, Loic, Goldberg, Mark S., Teo, Soo H., Yip, Cheng Har, Borresen-Dale, Anne-Lise, Zheng, Wei, Cai, Qiuyin, Winqvist, Robert, Pylkäs, Katri, Andrulis, Irene L., Devilee, Peter, Tollenaar, Rob A.E.M., García-Closas, Montserrat, Figueroa, Jonine, Hall, Per, Czene, Kamila, Brand, Judith S., Darabi, Hatef, Eriksson, Mikael, Hooning, Maartje J., Koppert, Linetta B., Li, Jingmei, Shu, Xiao-Ou, Zheng, Ying, Cox, Angela, Cross, Simon S., Shah, Mitul, Rhenius, Valerie, Choi, Ji-Yeob, Kang, Daehee, Hartman, Mikael, Chia, Kee Seng, Kabisch, Maria, Torres, Diana, Luccarini, Craig, Conroy, Don M., Jakubowska, Anna, Lubinski, Jan, Sangrajrang, Suleeporn, Brennan, Paul, Olswold, Curtis, Slager, Susan, Shen, Chen-Yang, Hou, Ming-Feng, Swerdlow, Anthony, Schoemaker, Minouk J., Simard, Jacques, Pharoah, Paul D.P., Kristensen, Vessela, Chenevix-Trench, Georgia, Easton, Douglas F., Dunning, Alison M., Edwards, Stacey L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2016
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Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065698/
https://ncbi.nlm.nih.gov/pubmed/27640304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.07.017
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