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Increasing Generality and Power of Rare-Variant Tests by Utilizing Extended Pedigrees
Recently, multiple studies have performed whole-exome or whole-genome sequencing to identify groups of rare variants associated with complex traits and diseases. They have primarily utilized case-control study designs that often require thousands of individuals to reach acceptable statistical power....
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| Publicado no: | Am J Hum Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065687/ https://ncbi.nlm.nih.gov/pubmed/27666371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.08.015 |
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