Nitrite-mediated reduction of macrophage NADPH oxidase activity is dependent on xanthine oxidoreductase-derived nitric oxide but independent of S-nitrosation

BACKGROUND: Inorganic nitrite has shown beneficial effects in cardiovascular and metabolic diseases partly via attenuation of NADPH-oxidase (NOX)-mediated oxidative stress. However, the exact mechanisms are still unclear. Here we investigated the role of S-nitrosation or altered expression of NOX su...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Zollbrecht, Christa, Persson, A. Erik G., Lundberg, Jon O., Weitzberg, Eddie, Carlström, Mattias
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065649/
https://ncbi.nlm.nih.gov/pubmed/27744114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.09.015
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