Impaired vascular function in sepsis-surviving rats mediated by oxidative stress and Rho-Kinase pathway

We investigated long-lasting changes in endothelial and vascular function in adult rat survivors of severe sepsis induced by cecal ligation and puncture (CLP) model. For this, male Wistar rats (200–350 g) had their cecum punctured once (non-transfixing hole) with a 14-gauge needle. Performed in this...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: de Souza, Priscila, Guarido, Karla Lorena, Scheschowitsch, Karin, da Silva, Luísa Mota, Werner, Maria Fernanda, Assreuy, Jamil, da Silva-Santos, José Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065648/
https://ncbi.nlm.nih.gov/pubmed/27744119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.09.016
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