Lack of association between dopaminergic antagonism and negative symptoms in schizophrenia: a positron emission tomography dopamine D(2/3) receptor occupancy study

RATIONALE: Several pre-clinical studies suggest that antipsychotic medications cause secondary negative symptoms. However, direct evidence for a relationship among antipsychotic medications, their direct effects on neurotransmitter systems, and negative symptoms in schizophrenia remains controversia...

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Udgivet i:Psychopharmacology (Berl)
Main Authors: Fervaha, Gagan, Caravaggio, Fernando, Mamo, David C., Mulsant, Benoit H., Pollock, Bruce G., Nakajima, Shinichiro, Gerretsen, Philip, Rajji, Tarek K., Mar, Wanna, Iwata, Yusuke, Plitman, Eric, Chung, Jun Ku, Remington, Gary, Graff-Guerrero, Ariel
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065392/
https://ncbi.nlm.nih.gov/pubmed/27557949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4415-6
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