The First Case of Severe Takotsubo Cardiomyopathy Associated with 5-Fluorouracil in a Patient with Abnormalities of Both Dihydropyrimidine Dehydrogenase (DPYD) and Thymidylate Synthase (TYMS) Genes

5-Fluorouracil (5-FU) is the backbone of the chemotherapy regimens approved for treatment of many malignancies, especially colorectal cancer (CRC). The incidence of cardiotoxicity associated with 5-FU ranges between 1.5% to 18% and is most commonly manifested as anginal symptoms. Cardiomyopathy is v...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cureus
Auteurs principaux: Saif, Muhammad W, Smith, Melissa, Maloney, Antonio
Format: Artigo
Langue:Inglês
Publié: Cureus 2016
Sujets:
Oncology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065345/
https://ncbi.nlm.nih.gov/pubmed/27752409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.783
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