Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope

The nuclear pore complex (NPC) mediates nucleocytoplasmic transport through the nuclear envelope. How the NPC assembles into this double membrane boundary has remained enigmatic. Here, we captured temporally staged assembly intermediates by correlating live cell imaging with high-resolution electron...

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Udgivet i:eLife
Main Authors: Otsuka, Shotaro, Bui, Khanh Huy, Schorb, Martin, Hossain, M Julius, Politi, Antonio Z, Koch, Birgit, Eltsov, Mikhail, Beck, Martin, Ellenberg, Jan
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065316/
https://ncbi.nlm.nih.gov/pubmed/27630123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19071
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