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Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope

The nuclear pore complex (NPC) mediates nucleocytoplasmic transport through the nuclear envelope. How the NPC assembles into this double membrane boundary has remained enigmatic. Here, we captured temporally staged assembly intermediates by correlating live cell imaging with high-resolution electron...

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Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Otsuka, Shotaro, Bui, Khanh Huy, Schorb, Martin, Hossain, M Julius, Politi, Antonio Z, Koch, Birgit, Eltsov, Mikhail, Beck, Martin, Ellenberg, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065316/
https://ncbi.nlm.nih.gov/pubmed/27630123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19071
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