Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope

The nuclear pore complex (NPC) mediates nucleocytoplasmic transport through the nuclear envelope. How the NPC assembles into this double membrane boundary has remained enigmatic. Here, we captured temporally staged assembly intermediates by correlating live cell imaging with high-resolution electron...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Otsuka, Shotaro, Bui, Khanh Huy, Schorb, Martin, Hossain, M Julius, Politi, Antonio Z, Koch, Birgit, Eltsov, Mikhail, Beck, Martin, Ellenberg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065316/
https://ncbi.nlm.nih.gov/pubmed/27630123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19071
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