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Trichostatin A Affects the Secretion Pathways of Beta and Intestinal Endocrine Cells

Histone deacetylase inhibitors (HDACi) were recently identified as having significant clinical potential in reversing β-cell functional inhibition caused by inflammation, a shared precursor of Type 1 and Type 2 diabetes. However, HDACi are highly complex and little is known of their direct effect on...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Cell Res
Hauptverfasser: Tiernan, Aubrey R, Champion, Julie A, Sambanis, Athanassios
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065249/
https://ncbi.nlm.nih.gov/pubmed/25305500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.09.031
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