Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae

The inability of native Saccharomyces cerevisiae to convert xylose from plant biomass into biofuels remains a major challenge for the production of renewable bioenergy. Despite extensive knowledge of the regulatory networks controlling carbon metabolism in yeast, little is known about how to reprogr...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Sato, Trey K., Tremaine, Mary, Parreiras, Lucas S., Hebert, Alexander S., Myers, Kevin S., Higbee, Alan J., Sardi, Maria, McIlwain, Sean J., Ong, Irene M., Breuer, Rebecca J., Avanasi Narasimhan, Ragothaman, McGee, Mick A., Dickinson, Quinn, La Reau, Alex, Xie, Dan, Tian, Mingyuan, Reed, Jennifer L., Zhang, Yaoping, Coon, Joshua J., Hittinger, Chris Todd, Gasch, Audrey P., Landick, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065143/
https://ncbi.nlm.nih.gov/pubmed/27741250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006372
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