Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer

Genome-wide association studies (GWAS) have identified many genetic susceptibility loci for colorectal cancer (CRC). However, variants in these loci explain only a small proportion of familial aggregation, and there are likely additional variants that are associated with CRC susceptibility. Genome-w...

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Published in:PLoS Genet
Main Authors: Gong, Jian, Hutter, Carolyn M., Newcomb, Polly A., Ulrich, Cornelia M., Bien, Stephanie A., Campbell, Peter T., Baron, John A., Berndt, Sonja I., Bezieau, Stephane, Brenner, Hermann, Casey, Graham, Chan, Andrew T., Chang-Claude, Jenny, Du, Mengmeng, Duggan, David, Figueiredo, Jane C., Gallinger, Steven, Giovannucci, Edward L., Haile, Robert W., Harrison, Tabitha A., Hayes, Richard B., Hoffmeister, Michael, Hopper, John L., Hudson, Thomas J., Jeon, Jihyoun, Jenkins, Mark A., Kocarnik, Jonathan, Küry, Sébastien, Le Marchand, Loic, Lin, Yi, Lindor, Noralane M., Nishihara, Reiko, Ogino, Shuji, Potter, John D., Rudolph, Anja, Schoen, Robert E., Schrotz-King, Petra, Seminara, Daniela, Slattery, Martha L., Thibodeau, Stephen N., Thornquist, Mark, Toth, Reka, Wallace, Robert, White, Emily, Jiao, Shuo, Lemire, Mathieu, Hsu, Li, Peters, Ulrike
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065124/
https://ncbi.nlm.nih.gov/pubmed/27723779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006296
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