Rapid Identification of Novel Inhibitors of the Human Aquaporin-1 Water Channel

Aquaporins (AQPs) are a family of membrane proteins that function as channels facilitating water transport in response to osmotic gradients. These play critical roles in several normal physiological and pathological states and are targets for drug discovery. Selective inhibition of the AQP1 water ch...

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Publicado no:Chem Biol Drug Des
Main Authors: Patil, Rajkumar V., Xu, Shouxi, van Hoek, Alfred N., Rusinko, Andrew, Feng, Zixia, May, Jesse, Hellberg, Mark, Sharif, Najam A., Wax, Martin B., Irigoyen, Macarena, Carr, Grant, Brittain, Tom, Brown, Peter, Colbert, Damon, Kumari, Sindhu, Varadaraj, Kulandaiappan, Mitra, Alok K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065099/
https://ncbi.nlm.nih.gov/pubmed/26685080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12713
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