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Achieving a physiological cortisol profile with once-daily dual-release hydrocortisone: a pharmacokinetic study

OBJECTIVE: Oral once-daily dual-release hydrocortisone (DR-HC) replacement therapy was developed to provide a cortisol exposure−time profile that closely resembles the physiological cortisol profile. This study aimed to characterize single-dose pharmacokinetics (PK) of DR-HC 5–20mg and assess intras...

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Detalhes bibliográficos
Publicado no:Eur J Endocrinol
Main Authors: Johannsson, Gudmundur, Lennernäs, Hans, Marelli, Claudio, Rockich, Kevin, Skrtic, Stanko
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065076/
https://ncbi.nlm.nih.gov/pubmed/27129362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-15-1212
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