The Effects of High-fat-diet Combined with Chronic Unpredictable Mild Stress on Depression-like Behavior and Leptin/LepRb in Male Rats

Leptin plays a key role in the pathogenesis of obesity and depression via the long form of leptin receptor (LepRb). An animal model of comorbid obesity and depression induced by high-fat diet (HFD) combined with chronic unpredictable mild stress (CUMS) was developed to study the relationship between...

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Vydáno v:Sci Rep
Hlavní autoři: Yang, Jin Ling, Liu, De Xiang, Jiang, Hong, Pan, Fang, Ho, Cyrus SH, Ho, Roger CM
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064321/
https://ncbi.nlm.nih.gov/pubmed/27739518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35239
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