The Effects of High-fat-diet Combined with Chronic Unpredictable Mild Stress on Depression-like Behavior and Leptin/LepRb in Male Rats

Leptin plays a key role in the pathogenesis of obesity and depression via the long form of leptin receptor (LepRb). An animal model of comorbid obesity and depression induced by high-fat diet (HFD) combined with chronic unpredictable mild stress (CUMS) was developed to study the relationship between...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Yang, Jin Ling, Liu, De Xiang, Jiang, Hong, Pan, Fang, Ho, Cyrus SH, Ho, Roger CM
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064321/
https://ncbi.nlm.nih.gov/pubmed/27739518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35239
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items