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Benzotriazole-Mediated Synthesis and Antibacterial Activity of Novel N-Acylcephalexins
Cephalexin (1) was acylated using N-acylbenzotriazoles (3a–k′) derived from various carboxylic acids including aromatic, heterocyclic and N-Pg-α-amino acid to afford N-acylcephalexins in excellent yields (82%–96%). Antibacterial screening of the novel cephalosporins revealed that all targets (4a–j)...
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| Publicado no: | Sci Pharm |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5064239/ https://ncbi.nlm.nih.gov/pubmed/28117314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/scipharm84030484 |
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