Expression of Phosphatase and Tensin Homologue, phospho-Akt, and p53 in Acral Benign and Malignant Melanocytic Neoplasms (Benign Nevi, Dysplastic Nevi, and Acral Melanomas)

BACKGROUND: The role of the phosphatidylinositol-3 kinase signaling pathway in the development of acral melanoma has recently gained evidence. Phosphatase and tensin homologue (PTEN), one of the key molecules in the pathway, acts as a tumor suppressor through either an Akt-dependent or Akt-independe...

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Detalhes bibliográficos
Publicado no:Ann Dermatol
Main Authors: Lyu, So Min, Wu, Ju Yeon, Byun, Ji Yeon, Choi, Hae Young, Park, Sang Hee, Choi, You Won
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064182/
https://ncbi.nlm.nih.gov/pubmed/27746632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5021/ad.2016.28.5.548
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