Assembly of Caenorhabditis elegans acentrosomal spindles occurs without evident microtubule-organizing centers and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1

Although centrosomes contribute to spindle formation in most cell types, oocytes of many species are acentrosomal and must organize spindles in their absence. Here we investigate this process in Caenorhabditis elegans, detailing how acentrosomal spindles form and revealing mechanisms required to est...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Wolff, Ian D., Tran, Michael V., Mullen, Timothy J., Villeneuve, Anne M., Wignall, Sarah M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063619/
https://ncbi.nlm.nih.gov/pubmed/27559133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-05-0291
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