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Reduced DNA double-strand break repair capacity and risk of squamous cell carcinoma of the head and neck – A case-control study

Tobacco and alcohol use play important roles in the etiology of squamous cell carcinoma of the head and neck (SCCHN). Smoking causes DNA damage, including double-strand DNA breaks (DSBs), that leads to carcinogenesis. To test the hypothesis that suboptimal DSB repair capacity is associated with risk...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Liu, Zhensheng, Liu, Hongliang, Gao, Fengqin, Dahlstrom, Kristina R., Sturgis, Erich M., Wei, Qingyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063601/
https://ncbi.nlm.nih.gov/pubmed/26963119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.02.003
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