Biodegradable mixed MPEG-SS-2SA/TPGS micelles for triggered intracellular release of paclitaxel and reversing multidrug resistance

In this study, a type of multifunctional mixed micelles were prepared by a novel biodegradable amphiphilic polymer (MPEG-SS-2SA) and a multidrug resistance (MDR) reversal agent (d-α-tocopheryl polyethylene glycol succinate, TPGS). The mixed micelles could achieve rapid intracellular drug release and...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Dong, Kai, Yan, Yan, Wang, Pengchong, Shi, Xianpeng, Zhang, Lu, Wang, Ke, Xing, Jianfeng, Dong, Yalin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063596/
https://ncbi.nlm.nih.gov/pubmed/27785018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S111930
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